Tetrabutylammonium Bromide CAS 1643-19-2


Free Sample Tetrabutylammonium Bromide CAS 1643-19-2
- Appearance:Powder
- Purity:99.8%
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Name: Tetrabutylammonium Bromide
CAS:1643-19-2
MOQ: 1KG
Directory Guidance on Tetrabutylammonium Bromide
Chemical Structure
Basic Info:
Melting point | 102-106 °C(lit.) |
Boiling point | 102 °C |
bulk density | 700kg/m3 |
density | 1.039 g/mL at 25 °C |
vapor pressure | 0Pa at 25℃ |
refractive index | n20/D 1.422 |
Fp | 100℃ |
Product Introduction:
Tetrabutylammonium Bromide is an important organic salt in chemical form (C₄H₉) ₄N + + Br⁻. It is a white crystalline solid, deliquing, stable at room temperature, and has a special odor. Tetrabutylammonium Bromide soluble in water, alcohol, ether and acetone and other solvents, slightly soluble in benzene, its molecular weight of 322.368, melting point between 102℃-118℃, refractive index of 1.422, density of 1.039 g/mL (25℃).
As a quaternary ammonium compound, Tetrabutylammonium Bromide has unique chemical properties. It can be completely dissociated into tetrabutylammonium cation and bromine ion in aqueous solution with A cationic radius of 4.94 A. Its ionic conductance in water is 1.953×10⁻³ m²/Ω·mol and 7.814×10⁻³ m²/Ω·mol (25℃). Its synthesis reaction is usually regarded as a second-order reaction, which may be carried out through the SN2 reaction mechanism, and the activated intermediate will be produced during the reaction process, which will affect the order degree and entropy change of the reaction.
Tetrabutylammonium Bromide has a wide range of applications in many fields. It is an efficient phase transfer catalyst, often used in two phase reaction systems, such as water-organic phase, can promote the transfer and reaction of reactants at the interface, thereby improving the reaction efficiency and selectivity. In organic synthesis, it can be used in processes such as alkylation, acylation and polymerization reactions, as an intermediate or catalyst. In addition, it is used as an electrolyte additive in electrochemical synthesis, and as a raw material for the preparation of surfactants and emulsifiers.
In industrial applications, Tetrabutylammonium Bromide is mainly used in pharmaceutical, chemical and electrochemical fields. In the pharmaceutical industry, it can be used to catalyze key steps in drug synthesis, such as the formation of carbon-nitrogen bonds and carbon-oxygen bonds. In chemical production, it is used to synthesize fine chemicals such as dyes, fragrances and polymer materials. Due to its toxicity, it is necessary to pay attention to safety protection when using, avoid contact with the skin and inhalation of dust, while storage should keep the container sealed, placed in a cool, dry place, to avoid contact with oxides and moisture.
Nature and Specifications:
Item | Specification |
Product Name | Tetrabutylammonium Bromide |
CAS No. | 1643-19-2 |
Appearance | Powder |
Shelf Life | 2 years |
Packing | As your requirements |
storage temp. | Store below +30°C. |
solubility | H2O: 0.1 g/mL, clear, colorless |
pka | 0[at 20 ℃] |
form | Crystalline Powder |
color | White to slightly cream |
Specific Gravity | 1.007 |
Product service:
- Certificate Of Analysis (COA)
- Material Safety Data Sheet (MSDS)
- Route of synthesis (ROS)
- Method of Aanlysis (MOA)
- Nuclear Magnetic Resonance (NMR)
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Tetrabutylammonium Bromide is a very important quaternary ammonium compound, which is used in many fields due to its excellent chemical properties. It is very important in organic synthesis, especially in phase transfer catalysis. It can enhance the transfer of reactants between the aqueous and organic phases, thereby improving the efficiency and selectivity of the reaction. For example, alkylation, acylation and polymerization reactions can use it as a catalyst to accelerate the reaction and reduce the possibility of side reactions. It has also been one of the most popular reagents in the preparation of fine chemicals, including dyes, fragrances and polymer materials, enabling complex routes in organic synthesis.
In the pharmaceutical field, Tetrabutylammonium Bromide is a key link in the process of many drug implants, it can efficiently catalyze the formation of carbon-nitrogen bonds and carbon-oxygen bonds, is one of the important reagents for the synthesis of antibiotics, antiviral drugs, cardiovascular drugs and other intermediates, its application greatly improves the efficiency and yield of drug synthesis. There is no substitute in medicine.
Tetrabutylammonium Bromide has important applications in the field of electrochemistry. It is a well-known electrolyte additive that can enhance the electrochemical performance of electrode materials and improve the conductivity and stability of batteries. It can also be used in electrochemical synthesis and electroplating to improve the uniformity and reaction efficiency of the coating, thus helping to promote the development of electrochemical technology.
Tetrabutylammonium Bromide has some surface activity and can be used to prepare surfactants and emulsifiers. In the cosmetics, coatings and food industries, it is used as a raw material for emulsifiers to produce stable emulsions and dispersions. This application is due to the fact that the hydrophobic and hydrophilic parts of its molecular structure enable it to play a fairly stable role between different phases.
In addition to these areas, Tetrabutylammonium Bromide is also of great importance in laboratory research. It is a reagent widely used to study the mechanism of phase transfer catalysis and organic reactions, which helps to better understand the phase transfer phenomenon in reaction processes and develop new catalytic systems. It is also used in analytical chemistry and can be used as a standard reagent for ion exchange and conductivity determination.
The use of Tetrabutylammonium Bromide is still expanding, for example in agriculture can be used to synthesize pesticide intermediates; In material science, it can be used as a template for preparing nanomaterials and porous materials. With the development of green chemistry and new energy technology, its application prospects are broader, and more optimized production processes and higher environmental protection requirements in the future will make it applied in more efficient and environmentally friendly fields.
Tetrabutylammonium Bromide has shown unique application value in the chemical field. Its catalytic performance is particularly outstanding, as a phase transfer catalyst, it can significantly improve the reaction efficiency of water-organic two-phase system. By promoting the transfer of reactants between phases, it not only accelerates the process of alkylation, acylation and polymerization, but also effectively inhibits side reactions, improves product selectivity and yield, and becomes an indispensable catalyst in organic synthesis.
The versatility of Tetrabutylammonium Bromide further expands its application scenarios. In addition to catalysis, it is not only a key reagent for the synthesis of nitrogen-containing compounds such as quaternary ammonium salt, but also widely used in the preparation of cosmetic emulsifiers, paint dispersants and food industry additives due to its surface activity. This versatility allows it to be used in chemical synthesis and industrial applications.
Excellent solubility provides convenience for the application of Tetrabutylammonium Bromide. White crystalline form Tetrabutylammonium Bromide can be simultaneously dissolved in water and alcohol, ether, acetone and other organic solvents, this cross-phase dissolution ability makes it flexible to adapt to different reaction system needs. Researchers can freely choose the solvent system according to the specific reaction environment, which greatly improves the flexibility of experimental design.
Under the background of the increasingly urgent need for environmental protection, Tetrabutylammonium Bromide shows significant green chemical properties. Its catalytic action can be achieved under mild conditions, greatly reducing the energy consumption and reaction pressure of the traditional process. This feature not only reduces the emission of three wastes, but also conforms to the concept of sustainable development and provides an environmentally friendly solution for chemical production.
For industrial applications, Tetrabutylammonium Bromide has penetrated a number of core areas. In the pharmaceutical industry, the construction of carbon-nitrogen/oxygen bonds catalyzed drug molecules, the electrochemical field as an electrolyte additive to improve the performance of energy storage devices, and the fine chemical industry to participate in the synthesis of dyes, fragrances and polymer materials, these applications fully reflect its technical value. With the development of new processes, its application is continuing to expand.
Stable chemical properties for the industrial application of Tetrabutylammonium Bromide laid the foundation. The characteristics of long-term preservation at normal temperature and pressure, combined with simple storage conditions (avoid light and moisture), make it have significant advantages in transportation and storage. This stability not only ensures the safety of use, but also reduces the cost of supply chain management.
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