2-Aminobenzimidazole CAS 934-32-7
Factory wholesale 2-Aminobenzimidazole CAS 934-32-7
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- Purity:99.8%
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Name: 2-Aminobenzimidazole
CAS: 934-32-7
MOQ: 1KG
Directory Guidance on 2-Aminobenzimidazole
Chemical Structure
Basic Info:
| Melting Point | 226-230 °C (lit.) |
| Boiling Point | 235.67°C (rough estimate) |
| Density | 1.1873 (rough estimate) |
| Refractive Index | 1.5341 (estimate) |
2-Aminobenzimidazole Introduction:
2-Aminobenzimidazole (2-0BZI) is a nitrogen-containing heterocyclic compound formed by the combination of benzene ring and imidazole rings in its molecular structure, connected by an amino group in their second position on each imidazole ring. This exceptional structural combination makes this compound both aromatic and reactive, making it an invaluable research object in both chemistry and materials science. Physical properties: C7H7N3 is typically seen as a white to light yellow crystalline powder with a melting point between 180degC and 185degC, and has low solubility in water but high solubility in polar solvents such as ethanol and methanol. Its molecular formula is C7H7N3, while its molecular weight is 133.15g/mol; its thermal stability and chemical inertness makes it unlikely to react significantly with air or moisture at room temperatures.
Traditional synthetic routes for 2-Aminobenzimidazole involve reacting o-phenylenediamine with either cyanamide or ammonium thiocyanate to achieve its formation. Under acidic conditions, o-phenylenediamine reacts with cyanamide to form a benzimidazole ring which then undergoes aminolysis or reduction reaction and introduces its amino group. Recent years, with the proliferation of green chemistry concepts, researchers have begun exploring more environmentally friendly synthetic routes – for instance using aqueous phase reactions or high-efficiency catalysts to minimize organic solvent usage. New technologies like microwave-assisted synthesis and solid-phase synthesis have significantly enhanced reaction efficiency, reduced production cycle time and lessened by-product generation – all to meet industrial standards for purity of product purity.
Chemical properties of 2-Aminobenzimidazole demonstrate its strong coordination ability by virtue of the amino group and nitrogen atom located on its imidazole ring; these elements allow it to form stable complexes with various metal ions and form stable complexes with them. Due to this property, ethylene takes an essential place in coordination chemistry and functional material development. Due to its weak alkalinity, amino groups are easily protonated in acidic environments, altering molecular polarity and solubility and changing how they behave in various reaction systems. Benzimidazole rings have an interlinked structure which makes them capable of participating in both p-p interactions and hydrogen bond network formation, two features which play a pivotal role in drug molecule design and can substantially improve binding capabilities with biological targets.
Nature and Specifications:
| Item | Specification |
| Product Name | 2-Aminobenzimidazole |
| CAS No. | 934-32-7 |
| Appearance | Powder |
| Shelf Life | 2 years |
| Packing | As Your Requirements |
| Solubility | <1g/l slightly soluble |
| Pka | 11.41±0.10(Predicted) |
| Form | Crystalline Powder, Crystals or Flakes |
| Color | Yellow to beige or light brown |
Product service:
- Certificate Of Analysis (COA)
- Material Safety Data Sheet (MSDS)
- Route of synthesis (ROS)
- Method of Aanlysis (MOA)
- Nuclear Magnetic Resonance (NMR)
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- Factory audit
The Application Situation Of 2-Aminobenzimidazole
The medical field is one of the most active application areas of 2-Aminobenzimidazole. As the core framework of antibacterial drug design, its derivatives can effectively control drug-resistant strains by inhibiting bacterial DNA rotase or topoisomerase IV and blocking the DNA replication process.Antivirals using molecules containing this structure may interfere with assembly of viral capsid proteins or functions like RNA polymerase which reduce replication efficiency for virus infections.
The pesticide industry also benefits from the unique properties of this compound. Fungicides with benzimidazole ring as the core have been widely used in the prevention and control of crop diseases. Their mechanism of action is mostly related to the destruction of tubulin polymerization of pathogenic bacteria, resulting in the obstruction of mycelial growth. In the field of insecticides, some derivatives can achieve efficient extermination of pests by inhibiting the activity of insect acetylcholinesterase or interfering with energy metabolism pathways. Furthermore, recent explorations in plant growth regulation have found that certain 2-Aminobenzimidazole derivatives can enhance the stress resistance of crops, such as improving their drought or salt-alkali resistance.
Attention to this compound in the field of materials science continues to heat up. Its excellent coordination ability makes it an ideal ligand for the synthesis of metal-organic framework (MOF) materials, which show broad prospects in fields such as gas adsorption, catalytic reactions and chemical sensing. For example, the adsorption efficiency of MOF materials based on 2-Aminobenzimidazole for carbon dioxide is significantly higher than that of traditional adsorbents, and it has important value in carbon capture technology. In the field of optoelectronic materials, polymers containing this structure can be used as the electron transport layer of organic light-emitting diodes (OLeds), and their rigid planar structure helps to improve the photoelectric conversion efficiency of the devices.
In the dye and pigment industry, 2-Aminobenzimidazole, as a key intermediate, is widely used in the synthesis of high-performance azo dyes and fluorescent materials. The amino groups in its molecules can enhance the affinity between the dye and the fiber, while the conjugated system can effectively extend the absorption wavelength of the chromophore and improve the color development intensity. Some derivatives exhibit strong fluorescence properties at specific excitation wavelengths and have been developed for use in biological imaging probes or anti-counterfeiting inks. In addition, the application of this compound in photosensitive materials has also attracted much attention, such as serving as a component of photoresist or a photoinitiator, playing a significant role in microelectronic processing.
The growth in demand in the field of electronic chemicals has opened up new markets for 2-Aminobenzimidazole. In lithium-ion batteries, its derivatives can be used as electrolyte additives to inhibit dendrite growth by forming a stable solid electrolyte interface film (SEI film), thereby extending the battery’s cycle life.Polymers use its rigid structure to increase heat resistance and mechanical strength of their materials for electronic packaging or coating in high temperature environments, and semiconductor manufacturing requires cleaning agents containing this compound that can effectively remove metal impurities on wafer surfaces thereby improving yield from chips produced.
The Advantages Of 2-Aminobenzimidazole
The core competitiveness of 2-Aminobenzimidazole comes from its highly modifiable and stable structure. The synergistic effect of the benzimidazole ring and the amino group enables the molecule to participate in a variety of reactions while remaining chemically inert under harsh conditions. For example, in high temperature or strong acid environments, the compound can still maintain the integrity of the active group, which makes it irreplaceable in industrial catalysis or extreme reaction systems. In addition, multiple reaction sites in the molecule provide flexible space for directional structural modification, and its physical and chemical properties can be precisely controlled by introducing different substituents.
Compatibility in cross-field applications is another outstanding advantage of 2-Aminobenzimidazole. The same basic structure can meet the differentiated needs of the pharmaceutical, pesticide, material and other industries after different modifications. For example, the introduction of hydrophilic groups in the pharmaceutical field can enhance the bioavailability of drugs, while the addition of hydrophobic chains in the pesticide field can improve leaf adhesion. This “one core, multiple uses” feature significantly reduces R&D costs, while shortening the new product development cycle, providing technical support for companies to seize market opportunities.
Environmental protection and safety characteristics make it more competitive in the context of stricter regulations. Compared with traditional chemicals containing heavy metals or persistent organic pollutants, 2-Aminobenzimidazole is more easily degraded in the environment and has lower toxicity to non-target organisms. The green synthesis process used in the production process further reduces the discharge of three wastes.
The maturity of the production process and cost advantages have further consolidated the market position of 2-Aminobenzimidazole. The raw materials of the traditional synthesis route are easily available, and the reaction conditions are mild, which is suitable for large-scale industrial production. In recent years, process optimization has significantly reduced energy consumption and waste emissions. For example, the use of continuous flow reaction technology can shorten the reaction time to 1/3 of the traditional process, while the product purity is increased to more than 99%. This high-efficiency and low-cost preparation method not only meets the demand for high-purity intermediates in the pharmaceutical field, but also provides a stable supply for emerging fields such as materials science.
The advantages in terms of economic benefits are also significant. Low raw material costs, high process maturity and wide application scenarios jointly support the price competitiveness of 2-Aminobenzimidazole. For downstream companies, the use of this compound can reduce the use of expensive additives and bring product premiums through performance optimization.For example, in the dye industry, its use as an intermediate can reduce energy consumption in the dyeing process; In the field of electronic materials, its addition can reduce the amount of precious metal catalysts used. This balance of cost and performance makes it a preferred functional chemical in multiple industrial fields.
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Chemicalbook-2-Aminobenzimidazole
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