Boron Trifluoride-Acetic Acid Complex CAS 373-61-5


Factory wholesale Boron Trifluoride-Acetic Acid Complex CAS 373-61-5
- Appearance:Liquid
- Purity:99.8%
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Name: Boron Trifluoride-Acetic Acid Complex
CAS: 373-61-5
MOQ: 1KG
Directory Guidance on Boron Trifluoride-Acetic Acid Complex
Chemical Structure
Basic Info:
Melting point | -47 °C |
Boiling point | 140-148 °C |
density | 1.353 g/mL at 25 °C(lit.) |
vapor pressure | 95Pa at 20℃ |
refractive index | n20/D 1.368(lit.) |
RTECS | ED2280000 |
Fp | 183 °F |
Product Introduction:
Boron Trifluoride-Acetic Acid Complex is an organic boron compound with the chemical formula C₂H₅BF₃O₂. It is a colorless, transparent liquid with a special smell, a relative density of about 1.26, and a boiling point of about 100°C. Boron Trifluoride-Acetic Acid Complex usually exists in the form of a complex because boron trifluoride is a Lewis acid that easily forms a stable complex with compounds containing lone pairs of electrons.
In esterification reactions, Boron Trifluoride-Acetic Acid Complex can promote the reaction between alcohol and acid, increase the reaction rate and yield; in alkylation reactions, it can activate the alkylating agent, making it easier to react with the substrate. In addition, it can also be used to synthesize some fluorine-containing organic compounds. By reacting with functional groups such as hydroxyl or amino groups in organic compounds, fluorine atoms are introduced, thereby changing the chemical properties and biological activity of the compounds.
Boron Trifluoride-Acetic Acid Complex has a wide range of applications in industry. In the field of medicine, it can be used to synthesize some drug intermediates. For example, in the synthesis of certain antibiotics, anti-tumor drugs and cardiovascular drugs, Boron Trifluoride-Acetic Acid Complex, as a catalyst or reaction reagent, can improve the synthesis efficiency and product quality. In the field of pesticides, it can be used to synthesize some high-efficiency and low-toxic pesticide intermediates to improve the efficacy and safety of pesticides. In addition, it also has certain applications in the fields of spices, dyes, fine chemicals, etc., such as being used to synthesize some spices compounds with special odors or dye compounds with specific colors.
Although Boron Trifluoride-Acetic Acid Complex has important value in chemical synthesis and industrial applications, its safety and environmental impact should be paid attention to during use. It is toxic and irritating to the skin and respiratory tract, so it is necessary to wear appropriate protective equipment such as gloves, goggles and masks during operation to avoid direct contact and inhalation.
Nature and Specifications:
Item | Specification |
Product Name | Boron Trifluoride-Acetic Acid Complex |
CAS No. | 373-61-5 |
Appearance | Liquid |
Shelf Life | 2 years |
Packing | As your requirements |
storage temp. | Store below +30°C. |
form | Liquid |
color | Clear light yellow to yellow-brown |
Water Solubility | reacts |
Product service:
- Certificate Of Analysis (COA)
- Material Safety Data Sheet (MSDS)
- Route of synthesis (ROS)
- Method of Aanlysis (MOA)
- Nuclear Magnetic Resonance (NMR)
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- Factory audit
1. Chemical synthesis field
Boron Trifluoride-Acetic Acid Complex, as a Lewis acid catalyst, has strong electrophilicity and acidity, and can effectively catalyze a variety of organic reactions. For example, in esterification reactions, it can promote the reaction between alcohol and acid, increase the reaction rate and yield. In addition, it is also used in alkylation, acylation, condensation and other reactions to help activate reactants and reduce the activation energy of the reaction. In recent years, the scientific research team has developed new synthetic methods using Boron Trifluoride-Acetic Acid Complex for the preparation of fluorinated organic compounds. These methods have mild conditions, good selectivity, and broad application prospects.
2. Pharmaceutical field
In pharmaceutical synthesis, Boron Trifluoride-Acetic Acid Complex is often used to synthesize drug intermediates. Fluorinated drugs are widely used in anti-tumor, antiviral, antibacterial and other fields due to their unique chemical properties and biological activity. Boron Trifluoride-Acetic Acid Complex can be used as a catalyst or reaction reagent to help introduce fluorine atoms or fluorinated groups, thereby improving the stability and bioavailability of drugs. For example, in the synthesis process of certain anti-tumor drugs and cardiovascular drugs, Boron Trifluoride-Acetic Acid Complex can significantly improve the synthesis efficiency.
3. Pesticide field
Fluorinated pesticides have become the development trend of the pesticide industry due to their high efficiency, low toxicity and low residue. Boron Trifluoride-Acetic Acid Complex can be used to synthesize fluorinated pesticide intermediates, such as fluorinated herbicides, fungicides, etc. These pesticides have broad application prospects in green agriculture, can effectively reduce environmental pollution, and improve the efficacy of pesticides.
4. Fine chemical field
Boron Trifluoride-Acetic Acid Complex is also widely used in fine chemicals. For example, in the synthesis of fragrances, it can be used to synthesize fluorinated fragrance compounds with special odors; in the dye industry, it can be used to synthesize high-performance fluorinated dyes, which have excellent light resistance, heat resistance and chemical stability. In addition, Boron Trifluoride-Acetic Acid Complex can also be used as a modifier for synthesizing polymer materials, and by introducing fluorinated groups, the corrosion resistance and weather resistance of the materials can be improved.
5. Other fields
Boron Trifluoride-Acetic Acid Complex can also be used as one of the raw materials for electronic special gases, and is used in ion implantation and doping processes in semiconductor manufacturing. It also plays an important role in display panel manufacturing. In addition, Boron Trifluoride-Acetic Acid Complex can also be used in the nuclear industry as one of the raw materials for boron neutron capture therapy (BNCT) for cancer treatment.
The biggest advantage of Boron Trifluoride-Acetic Acid Complex is its excellent Lewis acidity. It can efficiently catalyze a variety of organic reactions such as esterification, alkylation, acylation, condensation, etc., and can form stable complexes with electron donors (such as hydroxyl, amino, etc.) in the reactants, reduce the activation energy of the reaction, and increase the reaction rate and selectivity. It plays an irreplaceable role in organic synthesis, especially in the synthesis of fluorine-containing organic compounds, which can greatly improve the reaction efficiency.
Boron Trifluoride-Acetic Acid Complex is a stable liquid at room temperature with low volatility and high thermal stability. It is stable in a wide temperature range and is not easy to decompose. In addition, although boron trifluoride itself has certain toxicity, the acetic acid complex is safer and can be neutralized with aqueous solution, reducing the operational risk.
Boron Trifluoride-Acetic Acid Complex is not only a good catalyst, but also can be used as a reagent to directly participate in the reaction. It can add fluorine atoms or groups, thereby changing the chemical properties and biological activity of the compound. This versatility has a wide range of applications in pharmaceuticals, agrochemicals and specialty chemicals, such as introducing fluorine into drug intermediates, high-efficiency pesticides and high-performance dyes.
Boron Trifluoride-Acetic Acid Complex has good solubility in various solvents and is suitable for various reaction systems. It can remain in a gaseous state without decomposition at high temperatures. It has unique advantages in high-temperature reactions and nuclear industry applications. For example, in nuclear reactors, boron trifluoride is used as a neutron absorber to remain stable under extreme conditions to ensure the safety of nuclear reactions.
The preparation steps of Boron Trifluoride-Acetic Acid Complex are simple, low-priced, and easy to operate. For example, in the research of lithium/graphite fluoride primary batteries, boron trifluoride is used as an electrolyte additive, which can not only improve the discharge performance of the battery, but also has the advantages of simple operation and low cost. It is economical and practical, and is an economical and effective choice in industrial production.
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