Methoxypolyethylene Glycols CAS 9004-74-4
Free Sample Methoxypolyethylene Glycols CAS 9004-74-4
- Appearance:Powder
- Purity:99.8%
- Delivery:
30days - Sample Available:Available
- Payment:L/C,T/T,D/P,Paypal,Money Gram,Western Union
- Incoterm: FOB,CFR,CIF,EXW,FCA,CPT,CIP
- Transporta:Ocean, Land,Air, DHL，TNT FedEx
Name: Methoxypolyethylene Glycols
CAS: 9004-74-4
MOQ: 1KG
Directory Guidance on Methoxypolyethylene Glycols
Chemical Structure
Basic Info:
| Melting point | 60-64 °C |
| Boiling point | >200°C/760mmHg |
| density | 1.094 g/mL at 25 °C |
| vapor density | >1 (vs air) |
| vapor pressure | 0.05 mm Hg ( 20 °C) |
| refractive index | n20/D 1.459 |
Product Introduction:
Methoxyglycols (MPEG) is a class of non-ionic polymer compounds formed by rong-opening polymerization of ethylene oxide and methanol. Its chemical formula is CH3O(CH2CH2O)nH, where n represents the number of repeat units. These compounds have both hydrophilic pegylated segment and hydrophobic methyl terminal group, which makes them exhibit unique amphiphilicity in molecular structure. According to the different degree of polymerization, the molecular weight of Methoxypolyethylene Glycols can range from hundreds to tens of thousands of daltons, and the corresponding physical forms can be distributed from liquid to waxy solid. This molecular weight adjustability provides the basis for its adaptation in different application scenarios, making it an important functional raw material in the field of fine chemical industry.
From the perspective of chemical structure, the molecular main chain of Methoxypolyethylene Glycols is composed of repeated ethoxy units, and the methyl groups are connected by ether bonds at the end. This structure gives the material excellent solubility characteristics: soluble in water, alcohols, ketones and other polar solvents at room temperature, but the solubility of non-polar solvents is poor. The oxygen atoms in its molecular chain can form hydrogen bonds with water molecules, so it shows good water solubility, but with the increase of molecular weight, the influence of hydrophobic end groups gradually appears, resulting in the solubility of high polymerization degree products showing temperature sensitivity.
From the analysis of physical and chemical properties, the melting point of Methoxypolyethylene Glycols increased with the increase of molecular weight. When the molecular weight exceeded 2000, the material showed solid characteristics at room temperature. Its surface tension is significantly lower than that of pure water, and the surface tension of 20% aqueous solution is about 40-45mN/m, which makes it of special value in reducing interfacial tension. In terms of thermal stability, the material has no obvious decomposition phenomenon below 200℃, but it will be broken down in a strong oxidation environment. It is worth paying attention to the turbidity point property. When the temperature rises to the critical value, the aqueous solution will undergo reversible phase separation, which has important application value in the development of temperature-sensitive materials.
Biosafety is an important prerequisite for the wide application of Methoxypolyethylene Glycols. Acute toxicity test showed that its median lethal dose (LD50) was greater than 5000mg/kg (rat oral), which is actually non-toxic substances. In vitro cell experiments confirmed that the cell membrane structure would not be damaged at conventional concentrations. However, high molecular weight products may exhibit different metabolic behaviors in organisms, low molecular weight products can be rapidly excreted by the kidney, and polymers with molecular weight of more than 40,000 May be at risk of accumulation. Therefore, in practical applications, products with appropriate molecular weight specifications need to be selected according to the specific use.
Nature and Specifications:
| Item | Specification |
| Product Name | Methoxypolyethylene Glycols |
| CAS No. | 9004-74-4 |
| Appearance | Powder |
| Shelf Life | 2 years |
| Packing | As your requirements |
| Fp | 268 °C |
| storage temp. | -20°C |
| solubility | H2O: 50 mg/mL at 25 °C, clear, colorless |
| form | semisolid |
| Specific Gravity | 1.094 |
Product service:
- Certificate Of Analysis (COA)
- Material Safety Data Sheet (MSDS)
- Route of synthesis (ROS)
- Method of Aanlysis (MOA)
- Nuclear Magnetic Resonance (NMR)
- Packing pictures and loading video before loading
- Free Sample
- Factory audit
Methoxypolyethylene Glycols is the most commonly used biochemical raw material in pharmaceutical preparations. As a drug carrier, it can improve the solubility of insoluble drugs by physical or chemical means. In the development of injections, Methoxypolyethylene Glycols is often used as a stabilizer to inhibit the aggregation of protein drugs through steric hindrance. In recent years, its application in long-acting sustained-release preparations has attracted much attention. By controlling the molecular weight and modification sites of Methoxypolyethylene Glycols, the release kinetics of the drug can be precisely controlled. In the field of medical devices, Methoxypolyethylene Glycols coating can effectively reduce platelet adhesion on the surface of interventional devices, thereby improving their overall biocompatibility.
Among industrial additives, Methoxypolyethylene Glycols is a compound with multifunctional properties. As the basic component of lubricant, it makes the molecular chain of lubricant form an ordered adsorption layer on the metal surface, thereby reducing the friction coefficient. The compound can also be used as an initiator for polyurethane synthesis to regulate the mechanical properties of the material by changing the ratio of hard and soft segments. Their good dispersion makes them a major component of water treatment scale inhibitors, as they work by inhibiting the crystallization of calcium and magnesium salts. The additives modified by Methoxypolyethylene Glycols significantly improve the color uniformity and fastness in textile printing and dyeing, and have less harm to wastewater treatment.
The use of Methoxypolyethylene Glycols in personal care products continues to grow. In the formulation of cosmetics, it has the dual function of moisturizing agent and thickening agent; Methoxypolyethylene Glycols is often recommended as a surfactant precursor for the development of gel products, which can be modified by sulfonation or esterification to produce emulsifiers with different HLB values. Methoxypolyethylene Glycols derivatives can be used in hair care, can improve combing performance and form a film on the hair strands. Recently, its application in sunscreen products has made a breakthrough. The UV-absorbing groups can be covalently connected to the main chain of Methoxypolyethylene Glycols, thus greatly enhancing the water resistance of sunscreen.
In the field of polymer material modification, the grafting modification technology of Methoxypolyethylene Glycols is becoming more and more mature. The introduction of Methoxypolyethylene Glycols in the epoxy resin system can effectively regulate the cross-linking density of the cured material and improve the toughness of the material. After the copolymerization of Methoxypolyethylene Glycols, the hydrophilicity of polyester materials was significantly improved, which expanded its application space in biodegradable materials. In the process of synthesis of acrylic resin, copolymerization modification gives it long-term anti-fog performance, which is used in coating. In the rubber industry, the modified carbon black filler with Methoxypolyethylene Glycols can make it show better friction resistance.
New applications of Methoxypolyethylene Glycols in the field of environmental technologies continue to emerge. In wastewater treatment, the synergistic effect with inorganic flocculants can greatly improve the removal efficiency of suspended solids. In soil remediation projects, Methoxypolyethylene Glycols derivatives act as contaminant solubilizers to enhance the bioavailability of organic pollutants. The adsorption material modified by Methoxypolyethylene Glycols significantly improved the capture efficiency of volatile organic compounds. In the research and development of degradable plastics, Methoxypolyethylene Glycols chain segments are introduced to accelerate material hydrolysis and shorten the natural degradation cycle.
Excellent stability is the key factor for Methoxypolyethylene Glycols to be popular. Under normal storage conditions, the material is not easily oxidized or hydrolyzed, and the shelf life can reach more than three years. The wide pH tolerance range (3-11) ensures its stability in different media systems.
The unique biocompatibility of Methoxypolyethylene Glycols has established its position in the pharmaceutical industry. The material itself has no immunogenicity and will not trigger strong biological rejection reactions. Products with appropriate molecular weight selection can be effectively cleared by the kidneys, avoiding the risk of accumulation in the body. In terms of surface modification, the Methoxypolyethylene Glycols segment can effectively shield the immune recognition sites of the modified material, which is of great value in the development of long-acting formulations. The blood compatibility test shows that it does not cause significant coagulation reactions, which clears the obstacles for its application in the field of medical devices.
The mature preparation process provided support for the large-scale production of Methoxypolyethylene Glycols. Modern continuous production processes enable precise control of molecular weight distribution with less than 5% difference between batches. Advances in purification technology have reduced the content of key impurities (such as unreacted monomers, catalyst residues, etc.) to the ppm level. The quality control system comprehensively covers every link from raw materials to finished products, and the combined use of nuclear magnetic resonance, gel chromatography and other analytical means ensures that product parameters are accurate and controllable. These process advantages allow Methoxypolyethylene Glycols to achieve the best balance between cost and performance.
Environmentally friendly features meet the requirements of sustainable development. The closed cycle system is adopted in the production process, and the emission of three wastes is reduced by more than 80% compared with the traditional process. The product itself has good biodegradation, and the biodegradation rate can reach more than 75% in 28 days (OECD301B standard). In the application process, its use as an additive can significantly reduce the amount of other chemicals and indirectly reduce environmental pollution. Life cycle assessments show that Methoxypolyethylene Glycols’ carbon footprint is 30-40% lower than that of comparable petroleum-based products, and this environmental advantage is increasingly highlighted in the wave of green chemistry.
The wide application compatibility expands the market space of Methoxypolyethylene Glycols. Good compatibility with most organic solvents and resin systems makes it easy to integrate into existing production formulations. It shows excellent synergistic effect in the compounding system, and the compatibility with anionic and cationic auxiliaries reaches the industry standard. In terms of processing adaptability, it can be used alone or chemically modified as an intermediate. This high degree of application flexibility enables it to quickly respond to the technological innovation needs of different industries and continue to maintain market competitiveness.
Contact Us
Product Package picture：
Related References:
chemicalbook-Methoxypolyethylene Glycols
Pubchem-Methoxypolyethylene Glycols
Methoxypolyethylene Glycols Manufacturer
Contact Us
As an experienced Methoxypolyethylene Glycols manufacturer and supplier, Look Chemical is committed to producing and selling high quality products.
We cooperate and trade with 6000+ factories around the world, and our high-quality products and excellent services make us enjoy a high reputation internationally.
As Methoxypolyethylene Glycols CAS 9004-74-4 supplier, Look Chemical provides supply chain solutions to partners and customers in a wide range of industries. We offer competitive pricing and quality products.
If you have a demand for this product, please contact our company’s sales staff, we will provide you with a solution in the shortest time.
Transport proposal
1. For products ≤50kg, we recommend using express delivery, which is usually called DDU service (discounted, convenient).
2. For products ≤500kg, we generally recommend air freight, which is usually called FOB, CFR or CIF service (fast and efficient).
3. For products >500kg, we generally recommend shipping by sea, which is usually called FOB, CFR or CIF service (economical, safe).
4. For high-value products, please choose air or express to ensure the safety of product transportation.
Shandong Lookchemical service:
* Timely reply and 24 hours online, the professional team will provide you with the most favorable prices and high-quality products.
* The sample supports testing and inspection.
* Each batch of products will be tested to ensure that its quality meets user needs.
*Packaging can also be made according to customer requirements.
*Any inquiries will be answered by our relevant personnel within 24 hours.
*We will provide you with commercial invoice, packing list, packing list, COA, health certificate and certificate of origin if you need it. If your market has other special requirements, please let us know.
*We will monitor the logistics information in real time and will share the information with you.
* You can consult us at any time if you have any questions about the product, and we will answer you in time.
*If you have any questions about the product, you can report it to us, we will deal with it in time for you, and the product can be returned.
Contact Us
Frequently Asked Questions(FAQ):
We will make samples before mass production, and after sample approved, we’ll begin mass production. Doing 100% inspection during production, then do random inspection before packing.
Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
Yes. We’ll give you product analysis report before shipping.
Different quantity has different discount.
Yes. Welcome to visit.
You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
